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Cardiovascular Physiology Concepts

Richard E. Klabunde, PhD


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Cardiovascular Physiology Concepts
New Third Edition

Published by Wolters Kluwer, 2021
ISBN-13: 9781975150075

The third edition of this popular textbook, authored by Dr. Klabunde, stresses the fundamental concepts of cardiovascular physiology. It was written to enable students to learn how the cardiovascular system functions to build a foundation for understanding cardiovascular disease, its diagnosis and treatment. Therefore, the textbook is particularly well-suited for first- and second-year medical students, as well as students in allied health sciences and health profession training programs (e.g., nursing, physician assistant, cardiac rehabilitation, paramedic, exercise physiology and sports medicine). The textbook seamlessly integrates classical biophysical and biochemical principles with modern cellular physiology. These principles are placed into a clinical context by incorporating many pathophysiological examples and clinical cases.

The textbook comprises nine chapters (265 pages, 146 illustrations). Each chapter begins with a list of learning objectives. Chapters contain problems and clinical cases that reinforce physiologic principles. Each chapter concludes with a summary of key concepts, followed by self-assessment questions in a multiple-choice format with explanations.

The textbook chapter headings are listed below.

Chapter 1    Introduction to the Cardiovascular System
Chapter 2    Electrical Activity of the Heart
Chapter 3    Cellular Structure and Function
Chapter 4    Cardiac Function
Chapter 5    Vascular Function
Chapter 6    Neurohumoral Control of the Heart and Circulation
Chapter 7    Organ Blood Flow
Chapter 8    Exchange Function of the Microcirculation
Chapter 9    Cardiovascular Integration, Adaptation and Pathophysiology

In this third edition, many chapter sections have been rewritten to enhance clarity and to update our knowledge on specific topics. Added content includes material on cardiac electrophysiology during ischemia, the fetal circulation, and hemodynamic changes associated with coronary and peripheral artery disease. Over 40% of the figures have been revised or are new compared to the second edition.

This textbook can be purchased from in both print and Kindle versions by clicking on the link at right. 

I trust this textbook will become your first choice for learning Cardiovascular Physiology Concepts.


Richard E. Klabunde, Ph.D.
December 2020

DISCLAIMER: These materials are for educational purposes only, and are not a source of medical decision-making advice.