Peripheral Arterial Disease Tutorial

1. What are the relationships between pressure, flow and resistance for laminar and turbulent flow?
2. How do changes changes in vessel radius alter single vessel resistance?
3. What is a "critical stenosis" and why are large reductions in vascular radius required to reduce resting and maximal distal flows?
4. What are the hemodynamic consequences of single and multiple stenotic lesions in the leg?
5. Why might resting blood flows within a limb may be normal despite the presence of significant proximal stenotic lesions?
6. What is autoregulation of blood flow and what mechanisms may be responsible for this phenomenon?
7. What is active hyperemia and what mechanisms may be responsible for this phenomenon?
8. What is the ankle pressure index?  What is its normal value and under what conditions will this index fall during exercise and post-exercise?
9. What is the hemodynamic basis of "vascular steal?"
10. What is "intermittent claudication?"

Revised 11/03/06