-
What major coronary
vessels supply blood flow to the myocardium?
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-
What factors determine
coronary vascular tone?
click here
-
How and where is
nitric oxide formed in a coronary vessel and what is it physiological
role? click
here
-
What is active
hyperemia and what mechanisms are responsible for this phenomenon?
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-
How do sympathetic and
parasympathetic activation of the heart alter coronary blood flow?
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-
How do mechanical
forces during the cardiac cycle alter coronary blood flow?
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-
What determines oxygen
supply (delivery) to the myocardium?
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-
What determines the
degree of oxygen extraction from the coronary blood as it passes through
the heart? click here
-
How is myocardial
oxygen demand (consumption) determined?
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-
What is the myocardial
oxygen supply/demand ratio and what factors alter this ratio?
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-
How is the oxygen
supply/demand ratio related to the level of myocardial tissue
oxygenation? click
here
-
Define ischemia and
hypoxia. click here
-
How does myocardial
hypoxia alter electrical
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and mechanical function
click here?
-
What is coronary
autoregulation?
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-
What is a critical
stenosis? click
here
-
What is coronary
vascular steal?
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-
Define each of the
following and state the underlying cause: chronic stable angina,
Prinzmetal's (variant) angina, and unstable angina.
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-
What is the role of
endothelial dysfunction, particularly with respect to nitric oxide
production/bioavailability, in coronary artery disease and myocardial
ischemia?
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-
Define the following:
myocardial stunning, hibernation, preconditioning.
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Cardiovascular Physiology Concepts
